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Gene Expression Data
Assay Details
Assay
Reference: J:136720 Friedrichs M, et al., Lamination of the cerebral cortex is disturbed in Gli3 mutant mice. Dev Biol. 2008 Jun 1;318(1):203-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6383079
Gene symbol: Calb2
Gene name: calbindin 2
Results
Specimen 3E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex marginal layer Present Regionally restricted 3E Expression is in a single continuous row of cells on the basal cortical surface except for the dorsomedial telencephalon where several layers are detected.
Specimen 3J: embryonic day 12.5; Gli3Pdn/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS20: cerebral cortex marginal layer Present Regionally restricted 3J Expression is multilayered in this mutant compared to wild-type.
Specimen 3O: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex marginal layer Present 3O
Specimen 3T: embryonic day 14.5; Gli3Pdn/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS22: cerebral cortex marginal layer Present Regionally restricted 3T Expression is in dense clusters dorsomedially and is absent in the lateral marginal zone.
Specimen 4E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex marginal zone Present 4E' , 4E
TS27: cortical subplate Present 4E' , 4E
Specimen 4F: postnatal day 0; Gli3Pdn/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS27: cerebral cortex marginal zone Absent 4F' , 4F
TS27: cortical subplate Absent 4F' , 4F
TS27: neocortex Present Regionally restricted 4F' , 4F There is an ectopic cluster of positive fibers in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory