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Gene Expression Data
Assay Details
Assay
Reference: J:281430 Dong C, et al., Expression pattern of Kmt2d in murine craniofacial tissues. Gene Expr Patterns. 2019 Jun 19;34:119060
Assay type: RNA in situ
MGI Accession ID: MGI:6385118
Gene symbol: Kmt2d
Gene name: lysine (K)-specific methyltransferase 2D
Probe: Kmt2d cDNA1
Probe preparation: Antisense RNA
Results
Specimen 1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: frontal bone primordium Present 1B' , 1B
TS21: parietal bone primordium Present 1B' , 1B
TS21: choroid plexus Present 1B , 1B"
TS21: neocortex Present Regionally restricted 1B''' , 1B Expression was in the roof of the neopallial cortex.

Specimen 1C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: olfactory epithelium Present 1C
TS21: optic nerve Present 1C , 1C'
TS21: retina Present 1C , 1C'
TS21: pituitary gland Present 1C" , 1C
TS21: trigeminal ganglion Present 1C" , 1C

Specimen 1E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: frontal bone primordium Present 1E

Specimen 2B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: dura mater Present 2B
TS23: embryo ectoderm Present 2B
TS23: frontal bone primordium Present 2B Expression was detected in the osteoblasts.
TS23: parietal bone Present 2B Expression was detected in the osteoblasts.
TS23: tectum transversum Present Regionally restricted 2B Expression was detected in the tectum transversum chondrocytes.
TS23: cerebral cortex Present 2B Expression was in neurons.

Specimen 2C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lens Present 2C
TS23: retina Present 2C

Specimen 2D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: nasal septum Present Regionally restricted 2D Expression was detected in the ectoderm.

Specimen 2F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: frontal bone primordium Present 2F Expression was detected in osteoblasts.
TS23: lens Present 2F
TS23: brain Present 2F Expression was in neurons.

Specimen 2I: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: embryo ectoderm Present 2I
TS26: frontal bone Present 2I Expression was detected in osteoblasts.
TS26: parietal bone Present 2I Expression was detected in osteoblasts.
TS26: tectum transversum Present Regionally restricted 2I Expression was increased in the tectum transversum chondrocytes.
TS26: dura mater Present 2I Expression was increased compared to E15.5.

Specimen 2J: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain Present Widespread 2J
TS26: 3rd ventricle Present Clusters 2J Expression was clustered in the ependymal lining of the third ventricle.
TS26: diencephalon Present Clusters 2J Expression was clustered in the floor of the diencephalon.

Specimen 3B: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: frontal bone Weak 3B , 3B' Expression was dramatically decreased in the calvarial osteoblasts.
TS28: parietal bone Weak 3B , 3B' Expression was dramatically decreased in the calvarial osteoblasts.
TS28: face Present Regionally restricted 3B Expression was detected in a restricted pattern in the craniofacial epithelial cells next to the eye.

Specimen 3C: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: hair follicle Present 3C
TS28: retina Present 3C

Specimen 3D: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Present 3D

Specimen 3E: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: facial muscle Present Regionally restricted 3E Expression was detected in muscle cells adjacent to the interparietal bone.
TS28: face Present Regionally restricted 3E Expression was detected in craniofacial muscle cells, but not craniofacial epithelial cells adjacent to the interparietal bone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory