About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:272619 Aydogdu N, et al., TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827
Assay type: RNA in situ
MGI Accession ID: MGI:6385683
Gene symbol: Tshz3
Gene name: teashirt zinc finger family member 3
Probe: Tshz3 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S7H control: embryonic day 12.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS20: ureteral mesenchyme Present Non-Uniform S7H control The highest level of expression was in cells adjacent to the epithelium.
TS20: ureteral mesenchyme subepithelial layer Present S7H control
Specimen S7H Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl: embryonic day 12.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: ureteral mesenchyme Present Non-Uniform S7H Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl Expression appeared unchanged in the conditional mutant ureter.
TS20: ureteral mesenchyme subepithelial layer Present S7H Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl Expression appeared unchanged in the conditional mutant ureter.
Specimen S8 control: embryonic day 14.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Present Regionally restricted S8_control Tshz3 Expression was detected in smooth muscle cell progenitors.
Specimen S8 Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl: embryonic day 14.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Present Regionally restricted S8_ Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl Tshz3 Expression was unchanged in the conditional mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory