Hectd1 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:281315 D'Alonzo D, et al., Hectd1 is essential for embryogenesis in mice. Gene Expr Patterns. 2019 Jul 10;34:119064
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:6385697
Gene symbol:	Hectd1
Gene name:	HECT domain E3 ubiquitin protein ligase 1

Reporter:	lacZ
	Direct Detection

Results

2A ©

Specimen 2A: embryonic day 13.5; Hectd1^{Gt(RRC200)Byg}/Hectd1^{Gt(RRC200)Byg} (more

)

Structure	Level	Image	Note
TS21: labyrinthine zone	Present	2A	Reduced thickness compared with the wild-type.
TS28: placenta	Present	2A	Reduced thickness compared with the wild-type.
TS21: spongiotrophoblast	Present	2A	Thickness was similar as in the wild-type.

2B ©

Specimen 2B: embryonic day 13.5; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Image	Note
TS21: labyrinthine zone	Present	2B	Thickness was similar as in the wild-type.
TS21: spongiotrophoblast	Present	2B	Thickness was similar as in the wild-type.
TS28: placenta	Present	2B	Thickness was similar as in the wild-type.

4A ©

Specimen 4A: embryonic day 13.5; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS21: cardiac muscle tissue	Present		4A

4B ©

Specimen 4B: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: cardiac muscle tissue	Present		4B	The intercalated discs and the fascicles were stained as well.

4C ©

Specimen 4C: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: cardiac muscle tissue	Present		4C	The intercalated discs and the fascicles were stained as well.

4D ©

Specimen 4D: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: skeletal muscle	Present		4D

4E ©

Specimen 4E: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: epididymis	Present	Regionally restricted	4E	Expressed in the luminal side of the epithelial tissue over the head region.

4F ©

Specimen 4F: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: seminiferous cord		Weak		4F
TS28: Leydig cell	Leydig cell	Present		4F	Stronger staining.

4G ©

Specimen 4G: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: ovary follicle cell	Strong		4G
TS28: oocyte	Absent		4G

4H ©

Specimen 4H: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: oviduct	Strong	Regionally restricted	4H	Expressed in the ampulla of the Fallopian tubes.

4I ©

Specimen 4I: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: endometrium glandular epithelium	Strong		4I
TS28: endometrium stroma	Present		4I

4J1 ©

Specimen 4J1: embryonic day 13.5; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: placenta	Present	Widespread	4J1

4J2 ©

Specimen 4J2: embryonic day 13.5; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: placenta	Present	Widespread	4J2

4K ©

Specimen 4K: embryonic day 13.5; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS21: spongiotrophoblast	Present		4K

4L ©

Specimen 4L: embryonic day 13.5; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS21: labyrinthine zone	Present		4L

4M ©

Specimen 4M: embryonic day 13.5; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: decidua	Present		4M

4N ©

Specimen 4N: embryonic day 13.5; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS21: amnion	Present		4N

4O ©

Specimen 4O: embryonic day 13.5; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: placenta	Present	Regionally restricted	4O	Expressed in the fibrin-type fibrinoid.

5A ©

Specimen 5A: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: brain	Present	Widespread	5A

5B ©

Specimen 5B: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: retina ganglion cell layer	Present		5B

5C ©

Specimen 5C: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: urothelium of bladder	Weak		5C
TS28: detrusor muscle of bladder	Strong		5C

5D ©

Specimen 5D: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: intestine smooth muscle	Present		5D

5E ©

Specimen 5E: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: endometrium glandular epithelium	Present		5E

5F ©

Specimen 5F: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: mature renal corpuscle	Present		5F
TS28: renal tubule	Present		5F

5G ©

Specimen 5G: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: lobar bronchus	Strong		5G

5H ©

Specimen 5H: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: skin	Weak		5H

5I ©

Specimen 5I: postnatal day 21; Hectd1^{Gt(RRC200)Byg}/Hectd1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: skeleton	Present	Regionally restricted	5I	Expressed in the ossified regions.

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