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Gene Expression Data
Assay Details
Assay
Reference: J:265968 Mannion NM, et al., The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. Cell Rep. 2014 Nov 20;9(4):1482-94
Assay type: RT-PCR
MGI Accession ID: MGI:6386180
Gene symbol: Oas2
Gene name: 2'-5' oligoadenylate synthetase 2
Probe: Oas2-pA, Oas2-pB
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Values were expressed relative to wild type, which was set to one.
Results
Image: 3A Oas2 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex
wild type E11.5 TS19: embryo Present Not Specified; total RNA Not Specified Not Specified
Adar1-/- E11.5 TS19: embryo Present Not Specified; total RNA involves: 129S1/Sv * 129X1/SvJ * C57BL/6N Adartm2Phs/Adartm2PhsNot Specified
Adar1-/-;Ifnar1-/- E11.5 TS19: embryo Present Not Specified; total RNA involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6N Adartm2Phs/Adartm2Phs, Ifnar1tm1Agt/Ifnar1tm1AgtNot Specified
Adar1-/-;Mavs-/- E11.5 TS19: embryo Present Not Specified; total RNA involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N Adartm2Phs/Adartm2Phs, Mavstm1Tsc/Mavstm1TscNot Specified
Notes:
(a) Expression was highly elevated in Adar mutant embryos compared to wild type. Levels returned to normal in Adar;Ifnar1 double mutant embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
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