Gene Expression Data
Assay Details
Assay
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Reference:
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J:270238
Wang L, et al., Dynamic expression of p75(NTR) and Lingo-1 during development of mouse retinofugal pathway. Neurosci Lett. 2018 Sep 7;686:106-111
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6386238
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Gene symbol:
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Lingo1
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Gene name:
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leucine rich repeat and Ig domain containing 1
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Results
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Specimen
1D:
embryonic day 13.5
(more )
Specimen
1D:
(close )
Genetic Background:
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C57BL/6J
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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Structure |
Level |
Pattern |
Image |
Note |
TS21: retina |
Present |
Regionally restricted |
1D
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Expression was detected in neuroepithelial cells that appear to migrate from the basal layer to vitreal regions of the retina. Immunoreactivity was not observed in the optic fiber layer.
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Specimen
1E:
embryonic day 14.5
(more )
Specimen
1E:
(close )
Genetic Background:
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C57BL/6J
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Age:
|
embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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Structure |
Level |
Pattern |
Image |
Note |
TS22: retina |
Present |
Regionally restricted |
1E
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Expression was detected only in the ganglion cell layer with a weak signal in the optic fiber layer.
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Specimen
1F:
embryonic day 15.5
(more )
Specimen
1F:
(close )
Genetic Background:
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C57BL/6J
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Age:
|
embryonic day 15.5
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Gelatin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: retina |
Present |
Regionally restricted |
1F
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The immunostaining pattern was maintained at E15.5, showing a preferential localization in the soma of retinal ganglion cells.
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Specimen
2D:
embryonic day 13.5
(more )
Specimen
2D:
(close )
Genetic Background:
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C57BL/6J
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Age:
|
embryonic day 13.5
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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Structure |
Level |
Pattern |
Image |
Note |
TS22: optic disc |
Present |
Regionally restricted |
2D
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Expression was detected on glial profiles that wrap around optic axon bundles at the optic disc. Immunoreactivity was not detected on the axons.
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Specimen
2E:
embryonic day 14.5
(more )
Specimen
2E:
(close )
Genetic Background:
|
C57BL/6J
|
Age:
|
embryonic day 14.5
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
Sex:
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Not Specified
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Type:
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section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Gelatin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: optic disc |
Present |
Regionally restricted |
2E
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Expression was detected on glial profiles that wrap around optic axon bundles at the optic disc. Immunoreactivity was not detected on the axons.
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Specimen
2F:
embryonic day 15.5
(more )
Specimen
2F:
(close )
Genetic Background:
|
C57BL/6J
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Age:
|
embryonic day 15.5
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Gelatin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: optic disc |
Present |
Regionally restricted |
2F
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Expression was detected on glial profiles that wrap around optic axon bundles at the optic disc. Immunoreactivity was not detected on the axons.
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Specimen
4A:
embryonic day 13.5
(more )
Specimen
4A:
(close )
Genetic Background:
|
C57BL/6J
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Age:
|
embryonic day 13.5
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
Sex:
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Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Gelatin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: diencephalon |
Present |
Regionally restricted |
4B
,
4A
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Expression was detected in two cellular domains located caudally to the chiasm.
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Specimen
4C:
embryonic day 14.5
(more )
Specimen
4C:
(close )
Genetic Background:
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C57BL/6J
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Age:
|
embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Gelatin
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Specimen
4D:
embryonic day 15.5
(more )
Specimen
4D:
(close )
Genetic Background:
|
C57BL/6J
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Age:
|
embryonic day 15.5
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
|
Gelatin
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Specimen
4E:
embryonic day 15.5
(more )
Specimen
4E:
(close )
Genetic Background:
|
C57BL/6J
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Age:
|
embryonic day 15.5
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Gelatin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: optic chiasma |
Present |
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4E
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Expression was detected on axons.
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Specimen
4G:
embryonic day 13.5
(more )
Note: Double labeled: green - Lingo1; red - Fut4 (assay MGI:6386240).
Specimen
4G:
(close )
Genetic Background:
|
C57BL/6J
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Age:
|
embryonic day 13.5
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Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Gelatin
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Note:
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Double labeled: green - Lingo1; red - Fut4 (assay MGI:6386240).
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: optic chiasma |
Present |
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4G
,
4I
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Expression was detected on chiasmatic neurons, which co-localized SSEA-1 (Fut4) staining.
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