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Gene Expression Data
Assay Details
Assay
Reference: J:136705 Jonckheere N, et al., Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation. Dev Biol. 2008 Jun 15;318(2):224-35
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6386403
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-glucagon
Detection system: Cy3
Results
Specimen 3A: embryonic day 13.5 (more )
Note: Double labeled: green - Gcg; red - Pdx1 (assay MGI:6386392).
Structure Level Pattern Image Note
TS21: pancreas Present Regionally restricted 3A

Specimen 3B: embryonic day 13.5; Pygo2tm1.2Xdai/Pygo2tm1.2Xdai (more )
Note: Double labeled: green - Gcg; red - Pdx1 (assay MGI:6386392).
Structure Level Pattern Image Note
TS21: pancreas Present Regionally restricted 3B Authors report the relative number of expressing cells was similar to that of wild type littermates.

Specimen 4D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: endocrine pancreas Present Regionally restricted 4D

Specimen 4E: embryonic day 15.5; Pygo2tm1.2Xdai/Pygo2tm1.2Xdai (more )
Structure Level Pattern Image Note
TS23: endocrine pancreas Present Regionally restricted 4E Authors report no significant reduction in alpha cells compared to control littermates.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory