About   Help   FAQ
Sox9em1(cre/ERT2)Tchn
Endonuclease-mediated Allele Detail
Summary
Symbol: Sox9em1(cre/ERT2)Tchn
Name: SRY (sex determining region Y)-box 9; endonuclease-mediated mutation 1, Ting Chen
MGI ID: MGI:6386787
Synonyms: Sox9-CreER, Sox9-CreER
Gene: Sox9  Location: Chr11:112673050-112678586 bp, + strand  Genetic Position: Chr11, 77.27 cM
Alliance: Sox9em1(cre/ERT2)Tchn page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Sox9em1(cre/ERT2)Tchn expression driven by 1 gene
 
Mutation details: A cDNA encoding IRES-cre recombinase fused with a mutant form of estrogen receptor hormone-binding domain C (ERT2) was inserted after the site encoding the translational stop codon of the Sox9 gene, using the CRISPR/Cas9 technology. (J:269510, J:278073)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sox9 (mouse)
Summary of all recombinase alleles driven by Sox9.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox9 Mutation:  33 strains or lines available
References
Original:  J:269510 Xu Z, et al., Embryonic attenuated Wnt/beta-catenin signaling defines niche location and long-term stem cell fate in hair follicle. Elife. 2015 Dec 14;4:e10567
All:  17 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory