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Tg(Krt19-icre)2Hirt
Transgene Detail
Summary
Symbol: Tg(Krt19-icre)2Hirt
Name: transgene insertion 2, Hiroyuki Tomita
MGI ID: MGI:6387216
Synonyms: Krt19-iCre#2
Transgene: Tg(Krt19-icre)2Hirt  Location: unknown  
Alliance: Tg(Krt19-icre)2Hirt page
Transgene
origin
Strain of Origin:  B6D2F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Krt19-icre)2Hirt expression driven by 1 gene
 
Mutation details: Using bacterial recombineering technology, BAC RP24-68P2 containing the entire Krt19 was used to generate a transgene with a iCre-polyA cassette replacing the ATG codon and the following 632 bps of the coding sequence in the Krt19 gene. Twelve founder lines were generated. Line 2 and 5 heterozygous showed no health issue, and the line #2 was used for the studies. (J:279102)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt19 (mouse)
Summary of all recombinase alleles driven by Krt19.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:279102 Kanayama T, et al., Characterization of a BAC transgenic mouse expressing Krt19-driven iCre recombinase in its digestive organs. PLoS One. 2019;14(8):e0220818
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory