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Tg(NR1I2)4Gonz
Transgene Detail
Summary
Symbol: Tg(NR1I2)4Gonz
Name: transgene insertion 4, Frank Gonzalez
MGI ID: MGI:6388634
Synonyms: hPXR, huPXR
Transgene: Tg(NR1I2)4Gonz  Location: unknown  
Alliance: Tg(NR1I2)4Gonz page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA transgenic mouse line was created using a BAC clone containing the complete human gene sequence and including 5'- and 3'-flanking sequences. Lines 4 and 5 were generated (J:148160)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:148160 Ma X, et al., The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A. Drug Metab Dispos. 2007 Feb;35(2):194-200
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory