Gene Expression Data
Assay Details
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Assay
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Reference:
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J:174050
Rakic S, et al., Cortical interneurons require p35/Cdk5 for their migration and laminar organization. Cereb Cortex. 2009 Aug;19(8):1857-69
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6388778
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Gene symbol:
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Calb2
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Gene name:
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calbindin 2
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Antibody:
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Anti-Calretinin 7697
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
2D:
postnatal day 12
(more  )
Specimen
2D:
(close  )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6
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Age:
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postnatal day 12
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2E:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6
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Mutant Allele(s):
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Cdk5r1tm1Lht/Cdk5r1tm1Lht
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Age:
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postnatal day 12
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
Regionally restricted |
2E
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In the mutant, immunopositive neurons were most prominent in the lower and upper cortices above and below dispersed immunopositive axons.
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| TS28: cortical layer I |
Present |
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2E
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A significant increase in proportion of immunopositive cells accumulated in layer I of mutant mice compared with controls.
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Analysis Tools