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Tg(Hdnr-icre)betaPhg
Transgene Detail
Summary
Symbol: Tg(Hdnr-icre)betaPhg
Name: transgene insertion beta, Phillip Grote
MGI ID: MGI:6400491
Synonyms: Tg(5033428I22Rik-icre)betaPhg, tg(RP23-353N18,TSSHdnbetaiCre)Phg
Transgene: Tg(Hdnr-icre)betaPhg  Location: unknown  
Alliance: Tg(Hdnr-icre)betaPhg page
Transgene
origin
Mouse Generated:  Earliest citation of chimera generation: J:284123
Parent Cell Line:  F1H4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NTac)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Hdnr-icre)betaPhg expression driven by 1 gene
 
Mutation details: The transgene was made using BAC RP23-353N18 with the improves cre recombinase gene inserted downstream of the Hdnr beta isoform transcriptional start site. The transgene was inserted into a ROSA26R-lacZ reporter harboring mouse embryonic stem cell lines (mESCs). From these mESCs, embryos were generated by tetraploid morula aggregation and analyzed in three embryos derived. (J:284123)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Hdnr (mouse)
Summary of all recombinase alleles driven by Hdnr.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:284123 Ritter N, et al., The lncRNA Locus Handsdown Regulates Cardiac Gene Programs and Is Essential for Early Mouse Development. Dev Cell. 2019 Sep 9;50(5):644-657.e8
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory