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Krt6aem1(cre/ERT2)Tchn
Endonuclease-mediated Allele Detail
Summary
Symbol: Krt6aem1(cre/ERT2)Tchn
Name: keratin 6A; endonuclease-mediated mutation 1, Ting Chen
MGI ID: MGI:6401425
Synonyms: Krt6-CreER
Gene: Krt6a  Location: Chr15:101598363-101602746 bp, - strand  Genetic Position: Chr15, 56.97 cM
Alliance: Krt6aem1(cre/ERT2)Tchn page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Krt6aem1(cre/ERT2)Tchn expression driven by 1 gene
    CRISPR/Cas9 genome editing is used to insert an IRES-CreERT2-SV40poly cassette after exon 9. (J:285989)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt6a (mouse)
Summary of all recombinase alleles driven by Krt6a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Krt6a Mutation:  25 strains or lines available
References
Original:  J:285989 Lu Z, et al., Hair follicle stem cells regulate retinoid metabolism to maintain the self-renewal niche for melanocyte stem cells. Elife. 2020 Jan 3;9:e52712
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory