Myf5tm3Tajb
Targeted Allele Detail
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| Symbol: |
Myf5tm3Tajb |
| Name: |
myogenic factor 5; targeted mutation 3, Shahragim Tajbakhsh |
| MGI ID: |
MGI:6403683 |
| Synonyms: |
Myf5NH(loxP) |
| Gene: |
Myf5 Location: Chr10:107318769-107321995 bp, - strand Genetic Position: Chr10, 55.95 cM
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| Alliance: |
Myf5tm3Tajb page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:92799
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| Parent Cell Line: |
CK35 (ES Cell)
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| Strain of Origin: |
129S2/SvPas
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A targeting vector replaced the amino-terminal domain with a floxed neomycin and hygromycin resistance cassette upstream of the basic helix-loop-helix domain. The endogenous ATG was mutated to GTG, leaving the first ATG codons suitable for translation located in the chromatin remodeling and basic domains, at residues 69 and 82, respectively. This alleles was used to generate Myf5tm2Tajb.
(J:92799)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Myf5 Mutation: |
17 strains or lines available
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| Original: |
J:92799 Kassar-Duchossoy L, et al., Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant mice. Nature. 2004 Sep 23;431(7007):466-71 |
| All: |
1 reference(s) |
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Analysis Tools
