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Gene Expression Data
Assay Details
Assay
Reference: J:281795 Raju S, et al., Kinase domain dimerization drives RIPK3-dependent necroptosis. Sci Signal. 2018 Aug 21;11(544)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6404415
Gene symbol: Ripk3
Gene name: receptor-interacting serine-threonine kinase 3
Antibody: Anti-phospho-Rikp3 (GEN135-35-9)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1C Liver Ripk3+/D161N Ripk1+/+: embryonic day 11.5; Ripk3tm2Vmd/Ripk3+ (more )
Structure Level Pattern Image Note
TS19: liver Absent 1C Liver Ripk3+/D161N Ripk1+/+

Specimen 1C Liver Ripk3+/D161N Ripk1-/-: embryonic day 11.5; Ripk1tm1.1Vmd/Ripk1tm1.1Vmd, Ripk3tm2Vmd/Ripk3+ (more )
Structure Level Pattern Image Note
TS19: liver Present 1C Liver Ripk3+/D161N Ripk1-/- The Ripk3<+/D161N> Ripk1<-/-> embryos showed abnormal autophosphorylation in the liver.

Specimen 1C Placenta Ripk3+/D161N Ripk1+/+: embryonic day 11.5; Ripk3tm2Vmd/Ripk3+ (more )
Structure Level Pattern Image Note
TS28: placenta Absent 1C Placenta Ripk3+/D161N Ripk1+/+

Specimen 1C Placenta Ripk3+/D161N Ripk1-/-: embryonic day 11.5; Ripk1tm1.1Vmd/Ripk1tm1.1Vmd, Ripk3tm2Vmd/Ripk3+ (more )
Structure Level Pattern Image Note
TS28: placenta Present 1C Placenta Ripk3+/D161N Ripk1-/- The Ripk3<+/D161N> Ripk1<-/-> embryos showed abnormal autophosphorylation in the placenta.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory