Cyp1a1tm2025.1(CYP1A1)Arte
Targeted Allele Detail
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| Symbol: |
Cyp1a1tm2025.1(CYP1A1)Arte |
| Name: |
cytochrome P450, family 1, subfamily a, polypeptide 1; targeted mutation 2025.1, TaconicArtemis |
| MGI ID: |
MGI:6405045 |
| Gene: |
Cyp1a1 Location: Chr9:57595211-57611107 bp, + strand Genetic Position: Chr9, 31.34 cM
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| Alliance: |
Cyp1a1tm2025.1(CYP1A1)Arte page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:278424
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
C57BL/6NTac
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| Allele Type: |
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Targeted (Humanized sequence, Inserted expressed sequence, Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Cyp1a1tm2025.1(CYP1A1)Arte involves 1 genes/genome features (Cyp1a1)
View all
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Cyp1a1tm2025.1(CYP1A1)Arte expresses
1 gene
Knock-in expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CYP1A1 (1543) |
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Mutation details: The mouse coding sequence was replaced with the corresponding sequence for human CYP1A1 with insertion downstream of the 3' UTR of a polyadenylationsequence, FRT-flanked neyomysin resistance cassette and loxP site. Flp-mediated recombination removed the selection cassette.
(J:278424)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Cyp1a1 Mutation: |
39 strains or lines available
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| Original: |
J:278424 Kapelyukh Y, et al., Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice. Drug Metab Dispos. 2019 Aug;47(8):907-918 |
| All: |
2 reference(s) |
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Analysis Tools
