Cyp1a2tm2024.1(CYP1A2)Arte
Targeted Allele Detail
|
|
| Symbol: |
Cyp1a2tm2024.1(CYP1A2)Arte |
| Name: |
cytochrome P450, family 1, subfamily a, polypeptide 2; targeted mutation 2024.1, TaconicArtemis |
| MGI ID: |
MGI:6405047 |
| Gene: |
Cyp1a2 Location: Chr9:57584220-57590938 bp, - strand Genetic Position: Chr9, 31.3 cM
|
| Alliance: |
Cyp1a2tm2024.1(CYP1A2)Arte page
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:278424
|
| Parent Cell Line: |
Not Specified (ES Cell)
|
| Strain of Origin: |
C57BL/6NTac
|
|
| Allele Type: |
|
Targeted (Humanized sequence, Inserted expressed sequence, Null/knockout) |
| Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Cyp1a2tm2024.1(CYP1A2)Arte involves 1 genes/genome features (Cyp1a2)
View all
|
| |
|
Cyp1a2tm2024.1(CYP1A2)Arte expresses
1 gene
Knock-in expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CYP1A2 (1544) |
|
|
|
| |
|
Mutation details: THe coding sequence was replaced with the coresponding human Cyp1a2 sequence. A loxP site, F3-flanked neomycin resistance cassette, and human growth hormone polyadenylation sequence downstream of the 3' UTR. Flp-mediated recombination removed the selection cassette.
(J:278424)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Cyp1a2 Mutation: |
37 strains or lines available
|
|
| Original: |
J:278424 Kapelyukh Y, et al., Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice. Drug Metab Dispos. 2019 Aug;47(8):907-918 |
| All: |
2 reference(s) |
|
Analysis Tools
