Epcam<em1(cre/ERT2)Smoc> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6430709)

Epcam^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Epcam^{em1(cre/ERT2)Smoc}
Name:	epithelial cell adhesion molecule; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6430709
Synonyms:	Epcam-2A-CreERT2, Epcam^{em1(2A-CreERT2)Smoc}
Gene:	Epcam Location: Chr17:87943407-87958555 bp, + strand Genetic Position: Chr17, 57.87 cM
Alliance:	Epcam^{em1(cre/ERT2)Smoc} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Epcam^{em1(cre/ERT2)Smoc} expression driven by 1 gene

Mutation details: A 2A-CreERT2 co-expression cassette is inserted before the 3'UTR region of the Epcam gene via CRISPR/Cas mediated recombination. (J:238766)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Epcam (mouse) Summary of all recombinase alleles driven by Epcam. Alliance mouse Epcam gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Epcam Mutation:	33 strains or lines available

References

Original:	J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24