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Ace2em2(cre/ERT2)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Ace2em2(cre/ERT2)Smoc
Name: angiotensin converting enzyme 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
MGI ID: MGI:6430724
Synonyms: Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Gene: Ace2  Location: ChrX:162922338-162971414 bp, + strand  Genetic Position: ChrX, 76.12 cM, cytoband F5
Alliance: Ace2em2(cre/ERT2)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Ace2em2(cre/ERT2)Smoc expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 genome editing technology was used to insert a viral 2A oligopeptide that mediates ribosomal skipping and a Cre/ERT2-Wpre-polyA expression cassette into the gene stop codon. (J:238766)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ace2 (mouse)
Summary of all recombinase alleles driven by Ace2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ace2 Mutation:  66 strains or lines available
References
Original:  J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory