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Gene Expression Data
Assay Details
Assay
Reference: J:286046 Xu T, et al., Ablation of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development. J Cell Biochem. 2018 Jul;119(7):5852-5863
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6431058
Gene symbol: Dnmt3b
Gene name: DNA methyltransferase 3B
Antibody: anti-Dnmt3b (LS-B1191)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1A WT: embryonic day 18.5; Dnmt3btm5.1Enl/Dnmt3btm5.1Enl (more )
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted 1A WT There is ubiquitous expression in chondrocytes (both proliferating and hypertrophic).
Specimen 1A mutant: embryonic day 18.5; Dnmt3btm5.1Enl/Dnmt3btm5.1Enl, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted 1A Dnmt3bCol2 Expression is markedly reduced in chondrocytes compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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