Gene Expression Data
Assay Details
Assay
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Reference:
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J:278913
Meyer G, et al., Cajal-Retzius neurons are required for the development of the human hippocampal fissure. J Anat. 2019 Sep;235(3):569-589
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6441741
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Gene symbol:
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Trp73
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Gene name:
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transformation related protein 73
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Antibody:
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anti-p73alpha C-terminal
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
7C:
embryonic day 15.0
(more )
Specimen
7C:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Age:
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embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
7D:
embryonic day 15.0
(more )
Specimen
7D:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Age:
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embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS23: hippocampus |
Present |
Regionally restricted |
7D
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Expression in Cajal-Retzius neurons in dorsal hippocampus, appear directly continuous with expressing choroid plexus epithelial cells.
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TS23: lateral ventricle choroid plexus |
Present |
Regionally restricted |
7D
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Expression in epithelial cells.
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Specimen
7E:
embryonic day 15.0
(more )
Specimen
7E:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Age:
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embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS23: cortical hem |
Present |
Regionally restricted |
7E
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Expression in ventral cortical hem where Cajal-Retzius neurons for ventral hippocampal fissure are generated.
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Specimen
7E inset:
embryonic day 15.5
(more )
Specimen
7E inset:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Age:
|
embryonic day 15.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS23: cortical hem |
Present |
Regionally restricted |
7E inset
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Expression in ventral cortical hem at E15.5, when outmigrating of expressing cells reaches its maximum.
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Specimen
7F:
embryonic day 15.0
(more )
Specimen
7F:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Age:
|
embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS23: telencephalon |
Present |
Regionally restricted |
7F
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Expression in caudal hippocampal fissure.
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Specimen
9C:
postnatal day 1
(more )
Specimen
9C:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
9D:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Trp73tm1Fmc/Trp73tm1Fmc
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS27: hippocampal fissure |
Weak |
Single cells |
9D
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Expression in only a few Cajal-Retzius neurons in rudimentary superficial hippocampal fissure.
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Specimen
10A:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Trp73tm1(cre)Agof/Trp73tm1(cre)Agof
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS27: hippocampal fissure |
Weak |
Regionally restricted |
10A
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Expression in less numerous Cajal-Retzius neurons, irregularly distributed along hippocampal fissure, which appears shortened.
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Specimen
10B:
postnatal day 1
(more )
Specimen
10B:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
10C:
postnatal day 1
(more )
Specimen
10C:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
10D:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Trp73tm1Mak/Trp73tm1Mak
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS27: hippocampal fissure |
Present |
Regionally restricted |
10D
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Expression in a number of Cajal-Retzius neurons in ventral hippocampal fissure.
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TS27: hippocampus |
Present |
Regionally restricted |
10D
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Cajal-Retzius neurons almost absent in dorsal hippocampus.
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TS27: cerebral cortex marginal zone |
Absent |
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10D
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Cajal-Retzius neurons absent from medial cortical wall.
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Specimen
10E:
(close )
Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Trp73tm1(cre)Agof/Trp73tm1(cre)Agof
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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