Gene Expression Data
Assay Details
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Assay
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Reference:
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J:70485
Ciruna B, et al., FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev Cell. 2001;1(1):37-49
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6448447
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Gene symbol:
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Cdh1
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Gene name:
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cadherin 1
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Results
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Specimen
2A:
embryonic day 7.5
(more  )
Note: Double labeled: red - Cdh1; green - Ctnnb1 (assay MGI:6448451).
Specimen
2A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: red - Cdh1; green - Ctnnb1 (assay MGI:6448451).
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Specimen
2D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * ICR
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Mutant Allele(s):
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Fgfr1tm1Jrt/Fgfr1tm1Jrt
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: red - Cdh1; green - Ctnnb1 (assay MGI:6448451).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS10: primitive streak |
Present |
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2D
,
2F
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Mutant cells accumulating in the primitive streak, maintained high levels of expression at the cell membrane.
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Specimen
2G:
embryonic day 8.5
(more )
Note: Headfold stage.
Specimen
2G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Headfold stage.
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Specimen
2H:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * ICR
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Mutant Allele(s):
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Fgfr1tm1Jrt/Fgfr1tm1Jrt
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Headfold stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: embryo |
Present |
Regionally restricted |
2H
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Large masses of progenitor cells accumulated beneath the primitive streak expressing high levels of Cdh1 in a domain much larger than is normally found at the streak, and at greater levels than the overlying ectoderm.
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Specimen
2I:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * ICR
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Mutant Allele(s):
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Fgfr1tm1Jrt/Fgfr1tm1Jrt
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Headfold stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: embryo |
Present |
Regionally restricted |
2I
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Large masses of progenitor cells accumulated beneath the primitive streak expressing high levels of Cdh1 in a domain much larger than is normally found at the streak, and at greater levels than the overlying ectoderm.
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