Gene Expression Data
Assay Details
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Assay
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Reference:
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J:60591
Jablonka S, et al., Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: an animal model for spinal muscular atrophy type III. Hum Mol Genet. 2000 Feb 12;9(3):341-6
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6451039
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Gene symbol:
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Smn1
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Gene name:
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survival motor neuron 1
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Antibody:
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anti-Smn
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Detection system:
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Secondary antibody coupled to Cy3
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Results
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Specimen
1d:
postnatal month 6
(more  )
Specimen
1d:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spinal cord lumbar region |
Present |
Regionally restricted |
1d
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Expression is in the large motor neurons within the ventrolateral part of the lumbar spinal cord (L4).
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| TS28: spinal cord ventral horn |
Present |
Regionally restricted |
1d
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Expression is in the large motor neurons within the ventrolateral part of the lumbar spinal cord (L4).
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Specimen
1e:
postnatal month 6
(more )
Specimen
1e:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spinal cord lumbar region |
Present |
Regionally restricted |
1e
|
Expression is in the large motor neurons within the ventrolateral part of the lumbar spinal cord (L4).
|
| TS28: spinal cord ventral horn |
Present |
Regionally restricted |
1e
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Expression is in the large motor neurons within the ventrolateral part of the lumbar spinal cord (L4).
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Specimen
1f:
postnatal month 6; Smn1tm1Msd/Smn1 +
(more )
Specimen
1f:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Smn1tm1Msd/Smn1+
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spinal cord lumbar region |
Weak |
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1f
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Expression is in the large motor neurons within the ventrolateral part of the lumbar spinal cord (L4).
|
| TS28: spinal cord ventral horn |
Weak |
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1f
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Expression is in the large motor neurons within the ventrolateral part of the lumbar spinal cord (L4).
|
Specimen
1g:
postnatal month 6; Smn1tm1Msd/Smn1 +
(more )
Specimen
1g:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Smn1tm1Msd/Smn1+
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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|
Embedding:
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Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spinal cord lumbar region |
Weak |
Regionally restricted |
1g
|
Expression is in the large motor neurons within the ventrolateral part of the lumbar spinal cord (L4).
|
| TS28: spinal cord ventral horn |
Weak |
Regionally restricted |
1g
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Expression is in the large motor neurons within the ventrolateral part of the lumbar spinal cord (L4).
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