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Avpr1atm1.1(cre/GFP)Rpa
Targeted Allele Detail
Summary
Symbol: Avpr1atm1.1(cre/GFP)Rpa
Name: arginine vasopressin receptor 1A; targeted mutation 1.1, Richard D Palmiter
MGI ID: MGI:6451470
Gene: Avpr1a  Location: Chr10:122284404-122289357 bp, + strand  Genetic Position: Chr10, 70.36 cM, cytoband D3
Alliance: Avpr1atm1.1(cre/GFP)Rpa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:331457
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Avpr1atm1.1(cre/GFP)Rpa expression driven by 1 gene
 
Mutation details: A cassette encoding IRES-mnCre:GFP (an internal ribosome entry sequence (IRES), a Myc-tag and nuclear localization signals at the N-terminus of Cre recombinase, which is fused to green fluorescent protein followed by a SV40 polyadenylation sequence) was inserted just 3' of the termination codon in the last coding exon of the Avpr1a gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase. (J:101977)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Avpr1a (mouse)
Summary of all recombinase alleles driven by Avpr1a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Avpr1a Mutation:  35 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory