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Tacr3tm1.1(cre/GFP)Rpa
Targeted Allele Detail
Summary
Symbol: Tacr3tm1.1(cre/GFP)Rpa
Name: tachykinin receptor 3; targeted mutation 1.1, Richard D Palmiter
MGI ID: MGI:6451481
Gene: Tacr3  Location: Chr3:134534768-134640340 bp, + strand  Genetic Position: Chr3, 62.47 cM, cytoband H2
Alliance: Tacr3tm1.1(cre/GFP)Rpa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Tacr3tm1.1(cre/GFP)Rpa expression driven by 1 gene
 
Mutation details: A cassette encoding IRES-mnCre:GFP (an internal ribosome entry sequence (IRES), a Myc-tag and nuclear localization signals at the N-terminus of Cre recombinase, which is fused to green fluorescent protein followed by a SV40 polyadenylation sequence) was inserted just 3' of the termination codon in the last coding exon of the Tacr3 gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase. (J:101977)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tacr3 (mouse)
Summary of all recombinase alleles driven by Tacr3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tacr3 Mutation:  35 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
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