About   Help   FAQ
Htr2ctm1.1(icre)Jwso
Targeted Allele Detail
Summary
Symbol: Htr2ctm1.1(icre)Jwso
Name: 5-hydroxytryptamine (serotonin) receptor 2C; targeted mutation 1.1, Jong-Woo Sohn
MGI ID: MGI:6451570
Synonyms: Htr2ciCre
Gene: Htr2c  Location: ChrX:145745509-145980273 bp, + strand  Genetic Position: ChrX, 68.46 cM, cytoband D-F4
Alliance: Htr2ctm1.1(icre)Jwso page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:292866
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Htr2ctm1.1(icre)Jwso expression driven by 1 gene
 
Mutation details: A viral peptide bridge 2A sequence and the codon-improved Cre recombinase (iCre) were inserted into before the stop codon of Htr2c gene by homologous recombination in ES cells. (J:292866)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Htr2c (mouse)
Summary of all recombinase alleles driven by Htr2c.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Htr2c Mutation:  13 strains or lines available
References
Original:  J:292866 Park S, et al., A neural basis for tonic suppression of sodium appetite. Nat Neurosci. 2020 Mar;23(3):423-432
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory