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Tg(tetO-flpo)1Bbd
Transgene Detail
Summary
Symbol: Tg(tetO-flpo)1Bbd
Name: transgene insertion 1, Mariano Barbacid
MGI ID: MGI:6455673
Synonyms: TetO-FlpO
Transgene: Tg(tetO-flpo)1Bbd  Location: unknown  
Alliance: Tg(tetO-flpo)1Bbd page
Transgene
origin
Strain of Origin:  C57BL/6 x CBA
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(tetO-flpo)1Bbd expression driven by 1 gene
 
Mutation detailsThe expression of a codon-optimized Flp recombinase (Flpo) is driven by an inducible tetracycline response element and minimal promoter. (J:274213)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: tetO (bacteria)
Summary of all recombinase alleles driven by tetO.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:274213 Blasco MT, et al., Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF. Cancer Cell. 2019 Apr 15;35(4):573-587.e6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory