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Mafatm1.1(flpo)Gld
Targeted Allele Detail
Summary
Symbol: Mafatm1.1(flpo)Gld
Name: MAF bZIP transcription factor A; targeted mutation 1.1, Martyn Goulding
MGI ID: MGI:6459713
Gene: Mafa  Location: Chr15:75617339-75620077 bp, - strand  Genetic Position: Chr15, 34.82 cM
Alliance: Mafatm1.1(flpo)Gld page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:325444
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mafatm1.1(flpo)Gld expression driven by 1 gene
 
Mutation details: A Flp, WPRE sequence, and floxed PGK-Neo cassette were inserted into the locus. Cre-mediated recombination removed the selection cassette. (J:325444)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mafa (mouse)
Summary of all recombinase alleles driven by Mafa.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mafa Mutation:  20 strains or lines available
References
Original:  J:325444 Lecoin L, et al., Mafa-dependent GABAergic activity promotes mouse neonatal apneas. Nat Commun. 2022 Jun 7;13(1):3284
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory