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Pdgfratm2(cre/ERT2,-EGFP)Msas
Targeted Allele Detail
Summary
Symbol: Pdgfratm2(cre/ERT2,-EGFP)Msas
Name: platelet derived growth factor receptor, alpha polypeptide; targeted mutation 2, Masakiyo Sasahara
MGI ID: MGI:6467930
Synonyms: Pdgfra-CreERT2-Egfp, PR
Gene: Pdgfra  Location: Chr5:75312953-75358876 bp, + strand  Genetic Position: Chr5, 39.55 cM
Alliance: Pdgfratm2(cre/ERT2,-EGFP)Msas page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:250501
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Pdgfratm2(cre/ERT2,-EGFP)Msas expression driven by 1 gene
 
Mutation details: The Pdgfra promoter region drives expression of cre recombinase gene and enhanced green fluorescent protein (Egfp) gene. Cre is inserted after the promoter alelments and an internal ribosome entry site (IRES) sequence and EGFP sequence follows. (J:250501)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdgfra (mouse)
Summary of all recombinase alleles driven by Pdgfra.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdgfra Mutation:  88 strains or lines available
References
Original:  J:250501 Horikawa S, et al., PDGFRalpha plays a crucial role in connective tissue remodeling. Sci Rep. 2015 Dec 7;5:17948
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory