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Sox17tm3.1(cre/ERT2)Mgn
Targeted Allele Detail
Summary
Symbol: Sox17tm3.1(cre/ERT2)Mgn
Name: SRY (sex determining region Y)-box 17; targeted mutation 3.1, Mark A Magnuson
MGI ID: MGI:6470599
Synonyms: Sox17tm1.2(cre/ERT2)Mgn
Gene: Sox17  Location: Chr1:4561154-4567577 bp, - strand  Genetic Position: Chr1, 1.65 cM
Alliance: Sox17tm3.1(cre/ERT2)Mgn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:296396
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Sox17tm3.1(cre/ERT2)Mgn expression driven by 1 gene
 
Mutation details: Recombinase-mediated cassette exchange replaced the coding sequence with a cre/ERT2 fusing using the loxed cassette allele (LCA). Flp-mediated recombination removed the FRT-flanked hygromycin cassette. (J:296396)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sox17 (mouse)
Summary of all recombinase alleles driven by Sox17.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox17 Mutation:  29 strains or lines available
References
Original:  J:296396 Vanderbilt University, Labnodes. 2020;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory