Pdx1<tm4.1(cre)Mgn> Targeted Allele Detail MGI Mouse (MGI:6470616)

Pdx1^{tm4.1(cre)Mgn}
Targeted Allele Detail

Summary

Symbol:	Pdx1^{tm4.1(cre)Mgn}
Name:	pancreatic and duodenal homeobox 1; targeted mutation 4.1, Mark A Magnuson
MGI ID:	MGI:6470616
Synonyms:	Pdx1^creMgn
Gene:	Pdx1 Location: Chr5:147206907-147212658 bp, + strand Genetic Position: Chr5, 86.84 cM
Alliance:	Pdx1^{tm4.1(cre)Mgn} page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:296396
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Mutation
description

Allele Type:

Targeted (Recombinase)

Mutation:

Insertion

Pdx1^{tm4.1(cre)Mgn} expression driven by 1 gene

Mutation details: RMCE on the loxed cassette acceptor (LCA) allele inserted an exon1 with an inframe cre recombinase. The hygromycin resistance cassette was removed in the final allele. (J:296396)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdx1 (mouse) Summary of all recombinase alleles driven by Pdx1. Alliance mouse Pdx1 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Pdx1 Mutation:	35 strains or lines available

References

Original:	J:296396 Vanderbilt University, Labnodes. 2020;
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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