Sox17em1.1(phiC31*)Okn
Endonuclease-mediated Allele Detail
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| Symbol: |
Sox17em1.1(phiC31*)Okn |
| Name: |
SRY (sex determining region Y)-box 17; endonuclease-mediated mutation 1.1, Hideyuki Okano |
| MGI ID: |
MGI:6471921 |
| Synonyms: |
Sox172A-phiC31odeltaPuro |
| Gene: |
Sox17 Location: Chr1:4561154-4567577 bp, - strand Genetic Position: Chr1, 1.65 cM
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| Alliance: |
Sox17em1.1(phiC31*)Okn page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:284134
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
C57BL/6NCrlCrlj
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| Allele Type: |
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Endonuclease-mediated (Recombinase) |
| Mutation: |
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Insertion
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Sox17em1.1(phiC31*)Okn expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Sox17 (MGI:107543) |
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Mutation details: CRISPR-targeting introduced at the end of the coding sequence in exon 5 a GSG (Gly-Ser-Gly)-linker, porcine teschovirus-1 2A (P2A) peptide, SV40 virus NLS, phiC31o integrase gene, and puromycin resistance cassette flanked by FRT sites (FRT/F3/F5). Flp-mediated recombination removed the selection cassette.
(J:284134)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Sox17
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Sox17 Mutation: |
29 strains or lines available
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Lentiviral gene trap injected into zygotes.
ES cells = B6NJ-22(UTR) (C57BL/6NCrlCrlj)
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| Original: |
J:284134 Serizawa T, et al., Developmental analyses of mouse embryos and adults using a non-overlapping tracing system for all three germ layers. Development. 2019 Nov 4;146(21):dev174938 |
| All: |
1 reference(s) |
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Analysis Tools
