About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:288446 Christians A, et al., Inflammation-like changes in the urothelium of Lifr-deficient mice and LIFR-haploinsufficient humans with urinary tract anomalies. Hum Mol Genet. 2020 May 8;29(7):1192-1204
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6472985
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-Cdh1
Detection system: Alexa Fluor 555
Results
Specimen S2 +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Present S2_CDH1 +/+ Expressed in the adherens junction.
TS26: intermediate cell layer of ureter Present S2_CDH1 +/+ Expressed in the adherens junction.
TS26: superficial cell layer of ureter Present S2_CDH1 +/+ Expressed in the adherens junction.
Specimen S2 -/-: embryonic day 18.5; Lifrtm1Imx/Lifrtm1Imx (more )
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Present S2_CDH1 -/- Expressed in the adherens junction, same as in the wild-type.
TS26: intermediate cell layer of ureter Present S2_CDH1 -/- Expressed in the adherens junction, same as in the wild-type.
TS26: superficial cell layer of ureter Present S2_CDH1 -/- Expressed in the adherens junction, same as in the wild-type. Expression was dramatically downregulated in desquamated ureteric S-cells in the lumen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory