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Cyp26c1tm1Hmd
Targeted Allele Detail
Summary
Symbol: Cyp26c1tm1Hmd
Name: cytochrome P450, family 26, subfamily c, polypeptide 1; targeted mutation 1, Hiroshi Hamada
MGI ID: MGI:6473138
Gene: Cyp26c1  Location: Chr19:37674029-37681846 bp, + strand  Genetic Position: Chr19, 32.36 cM
Alliance: Cyp26c1tm1Hmd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119939
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  B6;129-Cyp26a1tm1.1Hmd/HmdRbrc
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: The targeting construct introduced upstream of exon 1 an FRT-flanked neomycin resistance cassette with a loxP site. (J:119939)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cyp26c1 Mutation:  23 strains or lines available
Notes
This allele was generated in ES cells containing Cyp26a1tm1.1Hmd
References
Original:  J:119939 Uehara M, et al., CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse. Dev Biol. 2007 Feb 15;302(2):399-411
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory