Gfi1tm2(GFP/cre/ERT2)Gan
Targeted Allele Detail
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| Symbol: |
Gfi1tm2(GFP/cre/ERT2)Gan |
| Name: |
growth factor independent 1 transcription repressor; targeted mutation 2, Lin Gan |
| MGI ID: |
MGI:6477586 |
| Synonyms: |
Gfi1-GCE |
| Gene: |
Gfi1 Location: Chr5:107864521-107873671 bp, - strand Genetic Position: Chr5, 52.23 cM
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| Alliance: |
Gfi1tm2(GFP/cre/ERT2)Gan page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:297267
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129S6/SvEv or C57BL/6J
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| Allele Type: |
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Targeted (Inducible, Recombinase, Reporter) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Gfi1tm2(GFP/cre/ERT2)Gan expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The coding sequence for P2A-GFP/cre/ERT2 and a downstream FRT-flanked neomycin resistance cassette was inserted in-frame to the C-terminus resulting in bicistronic expression of the endogenous transcript and a tamoxifen-inducible cre recombinase with green fluorescent protein reporter.
(J:297267)
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| Inheritance: |
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Not Specified |
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Gfi1
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gfi1 Mutation: |
31 strains or lines available
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| Original: |
J:297267 Tang Q, et al., Gfi1-GCE inducible Cre line for hair cell-specific gene manipulation in mouse inner ear. Genesis. 2019 Sep;57(9):e23304 |
| All: |
1 reference(s) |
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Analysis Tools
