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Gene Expression Data
Assay Details
Assay
Reference: J:158780 Li S, et al., SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells. BMC Dev Biol. 2010;10:19
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6479963
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-glucagon
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-glucagon MGI:6479912 may have been used in this assay.
Results
Specimen 1C: embryonic day 12.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: green - Glu (Gcg); red - Sel1l reporter (assay MGI:6479960).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Regionally restricted 1C Expression in endocrine lineage.
Specimen 1I: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: green - Glu (Gcg); red - Sel1l reporter (assay MGI:6479960).
Structure Level Pattern Image Note
TS23: endocrine pancreas Present 1I
Specimen 1K: postnatal day 1; Sel1lGt(CA0017)Wtsi/Sel1l+ (more )
Note: Double labeled: green - Glu (Gcg); red - Sel1l reporter (assay MGI:6479960).
Structure Level Pattern Image Note
TS27: endocrine pancreas Present 1K
Specimen 3A: embryonic day 11.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Pdx1 (assay MGI:6479966).
Structure Level Pattern Image Note
TS19: pancreas primordium epithelium Present Regionally restricted 3A Expression in alpha cells.
Specimen 3B: embryonic day 11.5; Sel1lGt(CA0017)Wtsi/Sel1lGt(CA0017)Wtsi (more )
Note: Double labeled: red - Glu (Gcg); green - Pdx1 (assay MGI:6479966).
Structure Level Pattern Image Note
TS19: pancreas primordium epithelium Present Regionally restricted 3B Expression in comparable number of cells as in wild type.
Specimen 3C: embryonic day 15.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Pdx1 (assay MGI:6479966).
Structure Level Pattern Image Note
TS23: endocrine pancreas Present Regionally restricted 3C Expression in alpha cells. Significant numbers of expressing cells detected.
Specimen 3D: embryonic day 15.5; Sel1lGt(CA0017)Wtsi/Sel1lGt(CA0017)Wtsi (more )
Note: Double labeled: red - Glu (Gcg); green - Pdx1 (assay MGI:6479966).
Structure Level Pattern Image Note
TS23: endocrine pancreas Weak Regionally restricted 3D Markedly reduced number of expressing cells compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
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