Dand5 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:93051 Marques S, et al., The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis. Genes Dev. 2004 Oct 1;18(19):2342-7
Assay type:	RNA in situ
MGI Accession ID:	MGI:6488528
Gene symbol:	Dand5
Gene name:	DAN domain family member 5, BMP antagonist

Probe:	cerl-2 probe1
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen 1A: embryonic day 7.0 (more

)
Note: Lateral view.

Structure	Level	Pattern	Image	Note
TS10: node	Present	Regionally restricted	1A	Expression first detected in a horseshoe-shaped pattern in perinodal region of early headfold stage embryo.

Specimen 1A': embryonic day 7.0 (more

)
Note: Anterior view.

Structure	Level	Pattern	Image	Note
TS10: node	Present	Regionally restricted	1A'	Expression first detected in a horseshoe-shaped pattern in perinodal region of early headfold stage embryo.

Specimen 1B: embryonic day 7.5 (more

)

Structure	Level	Pattern	Image	Note
TS11: node	Present	Regionally restricted	1B	By late headfold stage, expression decreased in intensity on left side and asymmetrically upregulated on right side of the node.

Specimen 1B': embryonic day 7.5 (more

)

Structure	Level	Pattern	Image	Note
TS11: node	Present	Regionally restricted	1B'	Asymmetrical expression in perinodal region.

Specimen 1C: embryonic day 8.0 (more

)

Structure	Level	Pattern	Image	Note
TS12: node	Present	Regionally restricted	1C	Asymmetrical expression becomes more evident at E8.0. Expression strongly detected on right side of node.

Specimen 1C': embryonic day 8.0 (more

)

Structure	Level	Pattern	Image	Note
TS12: node	Present	Regionally restricted	1C'	Asymmetrical expression in perinodal region.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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