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Gene Expression Data
Assay Details
Assay
Reference: J:178848 An CI, et al., Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6. BMC Dev Biol. 2011;11:59
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6491845
Gene symbol: Sox6
Gene name: SRY (sex determining region Y)-box 6
Antibody: Anti-Sox6
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1A Sox6f/f: embryonic day 18.5; Sox6tm2.1Vlf/Sox6tm2.1Vlf (more )
Note: Double labeled: red - Sox6; green - Myh7 (assay MGI:6491594).
Structure Level Pattern Image Note
TS26: extensor digitorum longus Present 1A Soxf/f Merge , 1A Sox6f/f Sox6
TS26: tibialis anterior Present 1A Soxf/f Merge , 1A Sox6f/f Sox6
Specimen 1A Sox6f/f;Myf5-cre: embryonic day 18.5; Myf5tm3(cre)Sor/Myf5+, Sox6tm2.1Vlf/Sox6tm2.1Vlf (more )
Note: Conditional mutant. Double labeled: red - Sox6; green - Myh7 (assay MGI:6491594).
Structure Level Pattern Image Note
TS26: extensor digitorum longus Absent 1A Sox6f/f;Myf5-Cre Sox6 , 1A Sox6f/f;Myf5-Cre Merge
TS26: tibialis anterior Absent 1A Sox6f/f;Myf5-Cre Sox6 , 1A Sox6f/f;Myf5-Cre Merge
Specimen 1B Sox6f/f: postnatal day 7; Sox6tm2.1Vlf/Sox6tm2.1Vlf (more )
Note: Double labeled: red - Sox6; green - Myh7 (assay MGI:6491594).
Structure Level Pattern Image Note
TS28: extensor digitorum longus Present 1B Soxf/f Merge , 1B Sox6f/f Sox6
TS28: tibialis anterior Present 1B Soxf/f Merge , 1B Sox6f/f Sox6
Specimen 1B Sox6f/f;Myf5-cre: postnatal day 7; Myf5tm3(cre)Sor/Myf5+, Sox6tm2.1Vlf/Sox6tm2.1Vlf (more )
Note: Conditional mutant. Double labeled: red - Sox6; green - Myh7 (assay MGI:6491594).
Structure Level Pattern Image Note
TS28: extensor digitorum longus Absent 1B Sox6f/f;Myf5-Cre Sox6 , 1B Sox6f/f;Myf5-Cre Merge
TS28: tibialis anterior Absent 1B Sox6f/f;Myf5-Cre Sox6 , 1B Sox6f/f;Myf5-Cre Merge
Specimen 1C Sox6f/f: postnatal month 4; Sox6tm2.1Vlf/Sox6tm2.1Vlf (more )
Note: Double labeled: red - Sox6; green - Myh7 (assay MGI:6491594).
Structure Level Pattern Image Note
TS28: extensor digitorum longus Weak Diffuse 1C Soxf/f Merge , 1C Sox6f/f Sox6
TS28: tibialis anterior Weak Diffuse 1C Soxf/f Merge , 1C Sox6f/f Sox6
Specimen 1C Sox6f/f;Myf5-cre: postnatal month 4; Myf5tm3(cre)Sor/Myf5+, Sox6tm2.1Vlf/Sox6tm2.1Vlf (more )
Note: Conditional mutant. Double labeled: red - Sox6; green - Myh7 (assay MGI:6491594).
Structure Level Pattern Image Note
TS28: extensor digitorum longus Absent 1C Sox6f/f;Myf5-Cre Sox6 , 1C Sox6f/f;Myf5-Cre Merge
TS28: tibialis anterior Absent 1C Sox6f/f;Myf5-Cre Sox6 , 1C Sox6f/f;Myf5-Cre Merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory