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Gene Expression Data
Assay Details
Assay
Reference: J:160146 Rowan S, et al., Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity. Genes Dev. 2010 May 15;24(10):980-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6502090
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Detection system: Cy3
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-Pax6 MGI:6502083 may have been used in this assay.
Results
Specimen 1B Prep1+/+ Pax6: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens primordium Present 1B Prep1+/+ Pax6 Expression in lens precursor cells.
Specimen 1B Prep1i/- Pax6: embryonic day 12.5; Pknox1Gt(OST71835)Lex/Pknox1tm1Ngc (more )
Structure Level Pattern Image Note
TS20: lens primordium Absent 1B Prep1i/- Pax6 Authors report that lens precursor cells did not form.
Specimen 1C E9.5 Prep1+/+ Pax6: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: lens pre-placode Present Regionally restricted 1C E9.5 Prep1+/+ Pax6 Expression in presumptive lens epithelium.
Specimen 1C E9.5 Prep1i/- Pax6: embryonic day 9.5; Pknox1Gt(OST71835)Lex/Pknox1tm1Ngc (more )
Structure Level Pattern Image Note
TS15: lens primordium Present Regionally restricted 1C E9.5 Prep1i/- Pax6 Initially expressed in presumptive lens epithelium.
Specimen 1C E10.5 Prep1+/+ Pax6: embryonic day 10.5; Pax6Sey-Neu/Pax6Sey-Neu (more )
Structure Level Pattern Image Note
TS17: lens pit Present Regionally restricted 1C E10.5 Prep1+/+ Pax6 Expression in presumptive lens epithelium.
Specimen 1C E10.5 Prep1i/- Pax6: embryonic day 10.5; Pknox1Gt(OST71835)Lex/Pknox1tm1Ngc (more )
Structure Level Pattern Image Note
TS17: lens primordium Absent 1C E10.5 Prep1i/- Pax6 Authors report lens prepacode fails to thicken or invaginate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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