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Gp1batm1.1(icre)Yose
Targeted Allele Detail
Summary
Symbol: Gp1batm1.1(icre)Yose
Name: glycoprotein 1b, alpha polypeptide; targeted mutation 1.1, Yotis A Senis
MGI ID: MGI:6504221
Synonyms: Gp1ba-Cre
Gene: Gp1ba  Location: Chr11:70529948-70532862 bp, + strand  Genetic Position: Chr11, 43.2 cM
Alliance: Gp1batm1.1(icre)Yose page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:273209
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Gp1batm1.1(icre)Yose expression driven by 1 gene
 
Mutation details: The targeting vector inserted a T2A sequence, improved cre recombinase gene inserted between the last amino acid of of the coding sequence and the termination sequence. Flp-mediated recombination removed an FRT-flanked puromycin resistance cassette inserted downstream of the stop codon. (J:273209)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gp1ba (mouse)
Summary of all recombinase alleles driven by Gp1ba.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gp1ba Mutation:  28 strains or lines available
References
Original:  J:273209 Nagy Z, et al., The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions. Blood. 2019 Jan 24;133(4):331-343
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory