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Oprk1tm2.1(icre/ERT2)Llch
Targeted Allele Detail
Summary
Symbol: Oprk1tm2.1(icre/ERT2)Llch
Name: opioid receptor, kappa 1; targeted mutation 2.1, Lee-Yuan Liu-Chen
MGI ID: MGI:6505539
Gene: Oprk1  Location: Chr1:5658689-5676354 bp, + strand  Genetic Position: Chr1, 1.89 cM, cytoband A2-A3
Alliance: Oprk1tm2.1(icre/ERT2)Llch page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:301305
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Oprk1tm2.1(icre/ERT2)Llch expression driven by 1 gene
 
Mutation details: A targeting vector was designed to insert a 2A:iCreER:sda-neo-sda cassette into the translational stop site. Th 2A oligopeptide sequence mediates ribosomal skipping. The Neo cassette is self-deleted in germ cells. (J:301305)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Oprk1 (mouse)
Summary of all recombinase alleles driven by Oprk1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oprk1 Mutation:  30 strains or lines available
References
Original:  J:301305 Liu-Chen L-C, Direct data submission for Oprk1 recombinase knockin. MGI Direct Data Submission. 2021;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory