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Tg(Cxcl12-icre/ERT2)L289Nono
Transgene Detail
Summary
Symbol: Tg(Cxcl12-icre/ERT2)L289Nono
Name: transgene insertion L289, Noriaki Ono
MGI ID: MGI:6508084
Synonyms: Cxcl12-creER
Transgene: Tg(Cxcl12-icre/ERT2)L289Nono  Location: unknown  Genetic Position: ChrUN, Syntenic
Alliance: Tg(Cxcl12-icre/ERT2)L289Nono page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Cxcl12-icre/ERT2)L289Nono expression driven by 1 gene
 
Mutation details: The bacterial artificial chromosome, RP23-22F6, containing 74 kb upstream and 121 kb downstream genomic sequences of the Cxcl12 gene was modified to insert (codon improved) icre/ERT2 fusion followed by bovine growth hormone and polyA cDNA into the first exon. (J:286719)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cxcl12 (mouse)
Summary of all recombinase alleles driven by Cxcl12.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:286719 Matsushita Y, et al., A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. Nat Commun. 2020 Jan 16;11(1):332
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory