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Lypd8tm1(cre)Ktak
Targeted Allele Detail
Summary
Symbol: Lypd8tm1(cre)Ktak
Name: LY6/PLAUR domain containing 8; targeted mutation 1, Kiyoshi Takeda
MGI ID: MGI:6508394
Synonyms: Lypd8tm1(cre,Venus)Ktak, Lypd8venus
Gene: Lypd8  Location: Chr11:58269869-58281365 bp, + strand  Genetic Position: Chr11, 36.19 cM, cytoband B2
Alliance: Lypd8tm1(cre)Ktak page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:232706
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase, Reporter)
Mutation:    Insertion
 
Lypd8tm1(cre)Ktak expression driven by 1 gene
 
Mutation details: Replacement of genomic fragment containing the third and fourth exons of the gene with a Cre recombinase gene, and internal ribosome entry site (IRES), a Venus gene and a neomycin-resistance gene cassette. (J:232706)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lypd8 (mouse)
Summary of all recombinase alleles driven by Lypd8.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lypd8 Mutation:  22 strains or lines available
References
Original:  J:232706 Okumura R, et al., Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia. Nature. 2016 Apr 7;532(7597):117-21
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory