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Cx3cr1em1(Ccre)Jung
Endonuclease-mediated Allele Detail
Summary
Symbol: Cx3cr1em1(Ccre)Jung
Name: C-X3-C motif chemokine receptor 1; endonuclease-mediated mutation 1, Steffen Jung
MGI ID: MGI:6508987
Synonyms: Cx3cr1ccre
Gene: Cx3cr1  Location: Chr9:119877749-119897362 bp, - strand  Genetic Position: Chr9, 71.37 cM
Alliance: Cx3cr1em1(Ccre)Jung page
Mutation
origin
Strain of Origin:  C57BL/6JOlaHsd
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Cx3cr1em1(Ccre)Jung expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 system inserted a cassette encoding a viral 2A oligopeptide (T2A) self-cleaving peptide, that mediates ribosomal skipping, fused to an C-terminal Cre recombinase fragment (CCre), directly downstream of the chemokine (C-X3-C motif) receptor 1 (Cx3cr1) gene. (J:302588)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cx3cr1 (mouse)
Summary of all recombinase alleles driven by Cx3cr1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cx3cr1 Mutation:  45 strains or lines available
References
Original:  J:302588 Kim JS, et al., A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages. Immunity. 2021 Jan 12;54(1):176-190.e7
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory