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Sall1em1(Ncre)Jung
Endonuclease-mediated Allele Detail
Summary
Symbol: Sall1em1(Ncre)Jung
Name: spalt like transcription factor 1; endonuclease-mediated mutation 1, Steffen Jung
MGI ID: MGI:6508988
Synonyms: Sall1ncre
Gene: Sall1  Location: Chr8:89753867-89770790 bp, - strand  Genetic Position: Chr8, 43.51 cM, cytoband D
Alliance: Sall1em1(Ncre)Jung page
Mutation
origin
Strain of Origin:  C57BL/6JOlaHsd
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Sall1em1(Ncre)Jung expression driven by 1 gene
 
Mutation detailsCRISPR/Cas9 system inserted a cassette encoding a viral 2A oligopeptide (T2A) self-cleaving peptide, that mediates ribosomal skipping, fused to an N-terminal Cre recombinase fragment (NCre), directly downstream of the spalt like transcription factor 1 (Sall1) gene. (J:302588)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sall1 (mouse)
Summary of all recombinase alleles driven by Sall1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sall1 Mutation:  78 strains or lines available
References
Original:  J:302588 Kim JS, et al., A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages. Immunity. 2021 Jan 12;54(1):176-190.e7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory