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Ddx4em1(cre/ERT2)Utr
Endonuclease-mediated Allele Detail
Summary
Symbol: Ddx4em1(cre/ERT2)Utr
Name: DEAD box helicase 4; endonuclease-mediated mutation 1, University of Tsukuba Laboratory Animal Resource Center
MGI ID: MGI:6509979
Synonyms: Ddx4CreERT2
Gene: Ddx4  Location: Chr13:112734867-112789009 bp, - strand  Genetic Position: Chr13, 63.87 cM
Alliance: Ddx4em1(cre/ERT2)Utr page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, No functional change, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Ddx4em1(cre/ERT2)Utr expression driven by 1 gene
 
Mutation details: A P2ACreERT2rGpA gene cassette was knockedin in-frame just before the stop codon. An extra 25 amino acid residues is added to Cterminal of the encoded protein after the ribosome skipping event. Three founders (#10, 42, 68) were generated. Line 10 was used for the study. (J:292649)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ddx4 (mouse)
Summary of all recombinase alleles driven by Ddx4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ddx4 Mutation:  59 strains or lines available
References
Original:  J:292649 Le HT, et al., Generation of B6-Ddx4(em1(CreERT2)Utr) , a novel CreERT2 knock-in line, for germ cell lineage by CRISPR/Cas9. Genesis. 2020 Jul;58(7):e23367
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory