Etv4 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:150712 Yaguchi Y, et al., Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072
Assay type:	RNA in situ
MGI Accession ID:	MGI:6511228
Gene symbol:	Etv4
Gene name:	ets variant 4

Probe:	Etv4 probe3
Probe preparation:	Antisense RNA
Assay notes:	These data are described in the text. The authors stated that Etv4 and Etv5 were expressed in an identical manner in the cerebellar anlage at E12.5, E16.5, P0, and P7 of development.

Results

Specimen not shown E12.5: embryonic day 12.5 (more

)

Structure	Level	Pattern	Note
TS20: cerebellum primordium	Strong
TS20: midbrain roof plate	Strong	Regionally restricted	Expression is in the posterior mesencephalon (developing inferior colliculus).
TS20: hindbrain	Strong	Regionally restricted	Expression is in rhombomere 1.
TS20: rhombic lip	Present	Regionally restricted	Expression is absent in the most posterior region.

Specimen not shown E16.5: embryonic day 16.5 (more

)

Structure	Level	Pattern	Note
TS24: cerebellum Purkinje cell cluster	Present
TS24: cerebellum ventricular layer	Present
TS24: cerebellum granule cell layer	Present		Expression was highest in the posterior region.
TS24: cerebellum	Present	Scattered

Specimen not shown P0: postnatal day 0 (more

)

Structure	Level	Pattern	Note
TS27: cerebellum Purkinje cell layer	Strong		The strongest expression is in Bergmann glia.
TS27: cerebellum external granule cell layer	Strong
TS27: cerebellum vermis lobule IX	Strong	Regionally restricted	Expression is in migrating granule cell precursors in the posterior cerebellum.
TS27: cerebellum vermis lobule VII	Strong	Regionally restricted	Expression is in migrating granule cell precursors in the posterior cerebellum.
TS27: cerebellum vermis lobule VIII	Strong	Regionally restricted	Expression is in migrating granule cell precursors in the posterior cerebellum.

Specimen not shown P7: postnatal day 7 (more

)

Structure	Level	Pattern	Note
TS28: cerebellum Purkinje cell layer	Present		Expression is stronger in Bergmann glia.
TS28: cerebellum internal granule cell layer	Strong	Regionally restricted	Expression is in granule cell precursors in the posterior internal granule layer.
TS28: cerebellum vermis lobule IX	Strong	Regionally restricted	Expression is higher in Bergmann glia and in granule cell precursors in the posterior internal granule layer.
TS28: cerebellum vermis lobule VII	Strong	Regionally restricted	Expression is higher in Bergmann glia and in granule cell precursors in the posterior internal granule layer.
TS28: cerebellum vermis lobule VIII	Strong	Regionally restricted	Expression is higher in Bergmann glia and in granule cell precursors in the posterior internal granule layer.

Specimen not shown P21: postnatal day 21 (more

)

Structure	Level	Pattern	Note
TS28: cerebellum Purkinje cell layer	Present
TS28: cerebellum granule cell layer	Present
TS28: cerebellum	Present	Regionally restricted	Expression is in Bergmann glia.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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