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Gcgem1(cre)Utr
Endonuclease-mediated Allele Detail
Summary
Symbol: Gcgem1(cre)Utr
Name: glucagon; endonuclease-mediated mutation 1, University of Tsukuba Laboratory Animal Resource Center
MGI ID: MGI:6512088
Synonyms: Gcg-Cre
Gene: Gcg  Location: Chr2:62304874-62313994 bp, - strand  Genetic Position: Chr2, 35.85 cM
Alliance: Gcgem1(cre)Utr page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Gcgem1(cre)Utr expression driven by 1 gene
 
Mutation details: A self-cleaving 2A-NLS-Cre gene sequence was inserted just before the stop codon via the CRISPR-Cas9 genome editing technology. (J:302484)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gcg (mouse)
Summary of all recombinase alleles driven by Gcg.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gcg Mutation:  34 strains or lines available
References
Original:  J:302484 Chang YH, et al., Uncovering the role of MAFB in glucagon production and secretion in pancreatic alpha-cells using a new alpha-cell-specific Mafb conditional knockout mouse model. Exp Anim. 2020 Apr 24;69(2):178-188
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory