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Tg(Hspa1b-flpo)A4Kht
Transgene Detail
Summary
Symbol: Tg(Hspa1b-flpo)A4Kht
Name: transgene insertion A4, Kazue Hashimoto-Torii
MGI ID: MGI:6512451
Synonyms: HSE-FLPo
Transgene: Tg(Hspa1b-flpo)A4Kht  Location: unknown  Genetic Position: Chr18, Syntenic
Alliance: Tg(Hspa1b-flpo)A4Kht page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Hspa1b-flpo)A4Kht expression driven by 1 gene
 
Mutation details: The transgenic construct contains a codon-optimized flp recombinase followed by a bGH polyadenylation (polyA) sequence under the direction of the murine heat shock response element (Hspa1b, formerly Hsp70-1) promoter/enhancer sequences .Founder line A4 was then selected for consistent expression. Analysis using shallow whole-genome sequencing suggests that the transgene integrated into an intronic region of the Tcerg locus on chromosome 18, and in the opposite orientation to the surrounding region. (J:303219)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Hspa1b (mouse)
Summary of all recombinase alleles driven by Hspa1b.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:303219 Mohammad S, et al., Long-term spatial tracking of cells affected by environmental insults. J Neurodev Disord. 2020 Dec 16;12(1):38
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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09/03/2024
MGI 6.24 		The Jackson Laboratory