Lamp1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:299228 De Pace R, et al., Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons. Cell Rep. 2020 Jun 16;31(11):107775
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6515587
Gene symbol:	Lamp1
Gene name:	lysosomal-associated membrane protein 1

Antibody:	anti-Lamp1 (1D4B)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

6A WT left ©

6A WT right ©

Specimen 6A WT: embryonic day 18.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: corpus callosum	Strong		6A WT right , 6A WT left

6A KO left ©

6A KO right ©

Specimen 6A KO: embryonic day 18.0; Borcs5^em1Jusb/Borcs5^em1Jusb (more

)

Structure	Level	Pattern	Image	Note
TS26: corpus callosum	Weak	Single cells	6A KO left , 6A KO right	Expression is mostly in a few glial cells.

7A WT LAMP1 ©

7A WT Merge ©

Specimen 7A WT: embryonic day 18.0 (more

)
Note: Triple labeled: green - Lamp1; blue - Sv2a (assay MGI:6515605); red - alpha-Bungarotoxin.

Structure	Level	Pattern	Image	Note
TS26: diaphragm	Present	Regionally restricted	7A WT Merge , 7A WT LAMP1	Expression is in neuromuscular junctions.

7A KO LAMP1 ©

7A KO Merge ©

Specimen 7A KO: embryonic day 18.0; Borcs5^em1Jusb/Borcs5^em1Jusb (more

)
Note: Triple labeled: green - Lamp1; blue - Sv2a (assay MGI:6515605); red - alpha-Bungarotoxin.

Structure	Level	Pattern	Image	Note
TS26: diaphragm	Absent		7A KO Merge , 7A KO LAMP1	Expression is absent in neuromuscular junctions.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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